In some cases, the vaccine was not specified. Epub 2022 Oct 17. 20052022 MedPage Today, LLC, a Ziff Davis company. Jakob Lillemoen Drivenes, MD, can be reached at jakobdrivenes@hotmail.com. Moderna and Pfizer COVID-19 vaccines are widely available options. RELATED:Moderna Caused This Reaction in 82 Percent of People, New Study Says. The median time to symptom resolution was 4 days. May 5, 2021. -18-24 hours later she developed 'hives'. Epub 2021 Nov 16. He joined MedPage Today in 2007. Delayed Localized Hypersensitivity Reactions to the Moderna COVID-19 Vaccine: A Case Series. A good character deserves a powerful name. In fact, for zolpidem (Ambien) in particular, the less often my patients need it, the happier I am. COVID-19 vaccines: comparison of biological, pharmacological characteristics and adverse effects of Pfizer/BioNTech and Moderna Vaccines. Sixteen patients at a private dermatology practice in Denmark developed delayed-onset urticaria after receiving COVID-19 vaccine boosters between February and June 2022, according to a letter . Does having a skin reaction to the Covid-19 vaccine mean you may react to other vaccines? Researchers recently looked at 414 skin reaction cases following COVID-19 vaccines between December and February and found that 83% came after Moderna shots, according to a paper published in the . Careers. diarrhea. and painful. Feeling unwell. Whilst it is uncertain whether PEG contained in mRNA vaccines may . You may opt-out by. All Rights Reserved. National Library of Medicine An official website of the United States government. "Never doubt that a small group of thoughtful, committed citizens can change the world. RELATED:Pfizer's Vaccine Protects You for at Least This Long, Study Finds. Of all vaccinations, 80.6% were of the Pfizer vaccine, while 18.7% were of Moderna. Registry participants collected information on the type and timing of vaccine doses and the morphology, timing, duration, and treatment of reactions. 2 Following implementation of vaccination, reports of . Palungwachira P, Vilaisri K, Musikatavorn K, Wongpiyabovorn J. Accessibility But some patients also are developing delayed skin reactions on other areas of the body after receiving one of the messenger RNA (mRNA) vaccines, which include one made by Pfizer-BioNTech. (Photo by Donato Fasano/Getty Images). This number dropped to 68 (0.2%) following the second dose of the vaccine. Leigh had her vaccine on March 12 and is still in pain from a rash two weeks later Credit: Media Scotland. I hope this information is helpful for you and your patient. Methods: In this study, 90 CSU patients vaccinated with one . Urticaria can include red patches in different parts of your body that include raised bumps. Public health efforts over the past few months have been aimed at vaccinating young adults. Epub 2022 Oct 18. -. Pitlick MM, Sitek AN, D'Netto ME, Dages KN, Chiarella SE, Gonzalez-Estrada A, Joshi AY, Park MA. 2021 Nov 1;42(6):515-521. doi: 10.2500/aap.2021.42.210075. The vaccines are very similar, but there must be something in the Pfizer your system reacts to. Disclaimer. Although true reactions to mRNA vaccines are rare, it is important to identify and distinguish between immediate hypersensitivity reactions and delayed urticarial reactions, as the immediate hypersensitivity reactions prompts postponing the subsequent vaccine dose, Drivenes said. Severe allergy-like reactions in at least eight people who received the COVID-19 vaccine produced by Pfizer and BioNTech over the past 2 weeks may be due to a compound in the packaging of the messenger RNA (mRNA) that forms the vaccine's main ingredient, scientists say. COVID VACCINE. If You Got Pfizer, You're More Likely to Have This Delayed Side Effect, Pfizer's Vaccine Protects You for at Least This Long, Study Finds, Moderna Caused This Reaction in 82 Percent of People, New Study Says, This Vaccine Reaction Means You May Have Already Had COVID, Study Says. The CDC agrees, saying that people who get a delayed rash on their arm after the first shot should still get the second shot. Information about both vaccine doses was available for 180 patients, 29 of whom had skin reactions after both doses. Read our coronavirus live blogfor the latest updates. Forty-eight hours after administration of the second dose, the . Background: The clinical effects of Pfizer-BioNTech coronavirus disease 2019 (COVID-19; BNT162b2) vaccine on the clinical course of chronic spontaneous urticaria (CSU) is unclear. Aims and Objectives: To evaluate the clinical effects of BNT162b2 vaccine on the clinical course of CSU. J Am Acad Dermatol. In most cases, the rash arose more than 24 hours after dosing (4.8% after the first dose, 4.9% after the second). However her presentation was delayed (18-24 hours), yet still urticarial/ itchy (and has lingered). New York State book online here or call 1-833-NYS-4-VAX; . 2023 American Academy of Allergy, Asthma & Immunology. 17.03.2021 09:55. -51 year old female patient (teacher, wants fully vaccinated ASAP). Bethesda, MD 20894, Web Policies Also, four patients were in clinical remission and receiving antihistamines and omalizumab. Similar to medications or foods, people can be allergic to a vaccine. Although all of these studies focused on the Moderna vaccine, such skin reactions have occurred with the Pfizer Covid-19 vaccine as well. It has lasted now for 2 weeks. Please enable it to take advantage of the complete set of features! Pescosolido E, Muller YD, Sabat-Bresc M, Ferrer M, Yerly D, Caubet JC, Lantin JP, Ribi C, Bergmann MM. You should be monitored for 30 minutes if: You have had a severe allergic reaction called anaphylaxis due to any cause. document.addEventListener( 'DOMContentLoaded', function() { WHYY thanks our sponsors become a WHYY sponsor. Before and transmitted securely. A health worker administers a dose of the Moderna Covid-19 vaccine on December 22, 2021 in Bari, [+] Italy. According to the case report, the rashes began one week after he had gotten the second dose of the Pfizer-BioNTech Covid-19 mRNA vaccine and then continued through the eight week mark. Nate Silver, the statistician and editor-in-chief of FiveThirtyEight, thinks Pfizer's delayed rollout of its COVID vaccine may have been politically motivated to hurt then-President Donald Trump . A pharmacist administers a dose of the Pfizer-BioNTech Covid-19 vaccine to a resident of the Brooklyn Center for Rehabilitation and Healthcare nursing home in New York on Jan. 5, 2021. Police "advise the public to not engage.". Booster shots. Sometimes, it can also become itchy. 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Source Reference: McMahon DE, et al "Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases" J Am Acad Dermatol 2021; DOI: 10.1016/j.jaad.2021.03.092. -She seems to fall between CDC guidelines in that she clearing is outside of the four hour window which would indicate immediate reaction (CBC guidelines indicate even without systemic symptoms, if hives develop within four hours, then a second dose should be avoided). Opens in a new tab or window, Visit us on Instagram. This is when a raised, itchy rash appears on the skin. All these symptoms developed between 1 day and 3 weeks (median, 14 days) after the booster was administered. Spikevax booster and delayed urticaria: a Swiss signal with diagnostic uncertainties due to a high proportion of direct patient reports. Overall, the median onset of systemic adverse events in the vaccine group in general was 1 to 3 days after either dose and lasted a median duration of 1 to 2 days. Along with it, there's a growing concern about a possible connection between the shingles virus and getting the COVID vaccine. Different vaccines can have different components. 2020 Feb 19;S0735-6757(20)30098-X. Urticaria rhymes with Hank Azaria, Kingdom of Bavaria, and I dont care-ia and is the medical term for hives. official website and that any information you provide is encrypted After reading your column, I chose Pfizer for my second booster. Delayed large local reactions occurred after 15% of first doses and after 18% of second doses. I fear that blaming office policy is either laziness or an attempt to deflect responsibility. Three hours after getting the COVID-19 Moderna vaccine Teresa Velasco's arm began to swell and a large red rash appeared. The CDC revealed that the cases have occurred "mostly in male adolescents and young adults age 16 years or older," with a median age of 30 after dose one, and 24 after dose two. The findings came from the COVID-19 Dermatology Registry, a joint effort of the American Academy of Dermatology (AAD) and the International League of Dermatologic Societies. The authors report no conflicts of interest pertaining to this article, MeSH Given that over 172 million Americans have received at least one COVID vaccine dose to date and only several hundred cases have been associated with heart inflammation, your personal odds of developing myocarditis or pericarditis are considered exceedingly rare. The second dose is often well tolerated. Therefore, testing for allergy is unnecessary. A research letter published in theNew England Journal of Medicine in April 2021did describe 12 patients who developed rashes after getting the Moderna Covid-19 vaccines. . Not uncommonly, skin reactions were accompanied by systemic effects, including fatigue, myalgia, headache, fever, arthralgia, nausea, and chills. Nine patients required antihistamines for treatment. 2022 Nov;52(11):1343-1346. doi: 10.1111/cea.14214. However, the data from this trial also revealed that 244 (0.8%) had "delayed skin reactions" after their first doses. with it more common in females. Others suffered from swelling or angioedema, which is the swelling of areas of tissue under the skin, sometimes affecting the face and throat. Different degrees of swelling may be present. These docs described 16 patients who had skin reactions two to 12 days (for a median of seven days) after receiving the first dose of the Moderna Covid-19 vaccine. "In the U.S., the Pfizer . This led to a discussion on a Danish mailing list for dermatologists about a possible relation to COVID booster vaccines, especially Moderna. Overall both vaccines seemed to produce a similar number of reactions in each cohort. Moderna and Pfizer COVID-19 vaccines are widely available options. Background: As the vaccination campaign in response to the coronavirus disease 2019 (COVID-19) pandemic continues, concerns with regard to adverse reactions to the vaccine remain. The coronavirus disease-2019 (COVID-19) outbreak was declared a pandemic by the World Health Organization on March 11, 2020, and development of a safe, effective COVID-19 vaccine rapidly became a global priority. Delayed reactions to the Covid vaccines are not due to allergy but rather due to the immunogenic effect of vaccination. She added that studies have indicated that the incidence of cutaneous adverse reactions following COVID-19 vaccination ranges from 1.0% to 1.9%, and that dermatologists have encountered a . Indeed, it is the only thing that ever has.". Late Hypersensitivity Reactions to the BNT162b2 SARS-CoV-2 Vaccine Are Linked to Delayed Skin Sensitization and Prior Exposure to Hyaluronic Acid. The side effect, dubbed Covid arm has occurred in a small number of patients in the US. Some are already calling it "COVID arm" to describe a delayed . Read on to find out what symptom to look out for, and what to do if it happens to you. Large rashes near the vaccine injection site were the most commonly . Dr. Blumenthal discussed this research letter and such cases in the following WCVB Channel 5 Boston news segment: Then there was the case series published in JAMA Dermatology from a Yale University School of Medicine team consisting of Margaret S. Johnston, MD, Anjela Galan, MD, Kalman L. Watsky, MD, and Alicia J. As of December 28, 2020, at least 10 allergic reactions to the Pfizer/BioNTech and two allergic reactions to Moderna vaccines have been reported. Local injection-site reactions occurred after 24% and 25% of first and second doses, respectively. Therfore, allergy testing for PEG may help provide further insight. Swollen lymph nodes. Opens in a new tab or window, Visit us on Twitter. Shock moment pet chimp is shot dead after mauling owner's daughter and savaging her arms and legs, In the Footsteps of Killers probe murder of Rita Ellis - strangled with her own undies and dumped in woods at RAF base, Queen says 'things are getting better' in first audience with Boris at Palace since start of Covid, Shocked owners found their beloved cats bleeding on their doorsteps after 'killing spree', Pope Francis greets Spider-Man at the Vatican after superhero swings by on his way to visit sick children in hospital, Kamala Harris is FINALLY set to visit Mexico border MONTHS after being put in charge of crisis as Trump also plans trip, Jill Biden BOOED on stage in Nashville as she slams Tennessee's low vaccine rate and insists 'you're booing yourselves'. NCI CPTC Antibody Characterization Program. And it doesnt have anything to do with 5G reception. Chronic spontaneous maculopapular urticaria on left forearm with raised, pruritic erythematous plaques that have presented daily for 30-60 minutes for the past eight weeks in widespread global hive formation. Epub 2021 Oct 24. None of skin reactions lasted longer than 14 days or prevented subsequent doses of the vaccine. Follow. BMC Infect Dis. Celldex published interim data on the drug in late June 2022, showing a 57.1% complete response rate after 12 weeks in the low-dose arm of 1.5 mg/kg. Side effects of the COVID-19 vaccine are usually mild and resolve on their own. MMWR Morb Mortal Wkly Rep. 2021 Aug 13;70(32):1094-1099. doi: 10.15585/mmwr.mm7032e4. These are mostly nothing to be concerned about, but can cause discomfort. The .gov means its official. Please refer to the AAAAI COVID-19 Task Force webpage for additional guidance. Pfizer pulls FDA request for Covid vaccine for kids under 5. In rare cases, the Pfizer vaccine has triggered inflammation of the heart. This data is presented in Table 8 below. The latest COVID tracking data shows that more than 29.1% of Americans have been fully vaccinated and about 42.7% have gotten their first dose so far. Have you heard of other cases of hives caused by the Pfizer vaccine? The purpose of this study is to investigate chronic spontaneous urticaria (CSU) flares triggered by COVID-19 vaccines in patients with well controlled CSU. Most side effects go away in a few days. Cureus is on a mission to change the long-standing paradigm of medical publishing, where submitting research can be costly, complex and time-consuming. Please enable it to take advantage of the complete set of features! But they stressed that people with the harmless reaction should still get their second dose of the jab for optimal protection against Covid - around 95 per cent for the Moderna jab. chronic; covid-19 vaccine complication; erythematous plaques; hives; pfizer-biontech vaccine; spontaneous urticaria. Johnston MS, Galan A, Watsky KL, Little AJ. Even if the side effect were linked to the vaccine, a single case report wont tell you how rare the side effect may be. Clin Exp Allergy. Bookshelf It may not be super common. No serious reactions were reported. Opens in a new tab or window, Visit us on Facebook. In fact, a majority of severe allergic reactions will happen within 15 minutes of the shot. A randomized controlled trial of adding intravenous corticosteroids to H1 antihistamines in patients with acute urticaria. Delayed reactions like So's aren't typical, and they may not be definitively associated with the vaccine. One patient later developed cutaneous lymphocytic vasculitis. Would you like email updates of new search results? Instead, it describes a whole set of immune system responses that dont begin until at least 12 hours after its encountered a potential invader. If you're eating this food, it could make your hair loss worse as you age. eCollection 2022. Recipients of the Moderna vaccine have also reported these symptoms following vaccination, though at lower rates. Seven patients had only one positive skin test, while seven others had several positive results. He admonished my boyfriend for not taking the medication, which I found odd. -Allergy history includes mild allergic rhinitis (dander, dust mite), itching with Vicodin and Latex in the past, reaction to MRI contrast in the past (itching, swelling, nausea, vomiting, hives). Experts explain that as COVID-19 infection rates rose throughout . You wont need antibiotics unless any of your skin gets infected with bacteria. Journal of the American Academy of Dermatology. Share on Facebook. Clin Transl Allergy. Erythromelalgia occurred after 5.9% of second doses, and cosmetic filler reactions occurred after 4.9% of second doses. Epub 2022 Sep 27. Maculopapular Urticaria on Left Forearm, Chronic spontaneous maculopapular urticaria on left forearm with, MeSH The second dose is often well tolerated. No other type of reaction occurred in more than 1%-2% of patients after either dose. "Pain in the night and a little red," said Teresa Velasco, San Francisco . All Rights Reserved. If they dont, call your doctor, a real medical doctor. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Advance Local. Privacy Policy This site needs JavaScript to work properly. Ambien increases risk of both falling and motor vehicle accidents. While myocarditis and pericarditis can be serious, the CDC has shared that in COVID vaccine-related cases, "most patients who received care responded well to medicine and rest and quickly felt better." Six required acute doctor visits, and four were admitted to the ED. Your boyfriend would be right to contest the bill, which was medically unnecessary. In contrast, the vast majority of the reported potentially serious systemic allergic reactions to the mRNA COVID-19 vaccines have occurred within 30 minutes of vaccination (most within 15 minutes). Than 14 days ) after the booster was administered rhymes with Hank Azaria, Kingdom of,! Especially Moderna symptom resolution was 4 days whom had skin reactions have occurred with the Pfizer has... Was 4 days and omalizumab this food, it could make your hair loss worse as you age ;. With one local reactions occurred after 15 % of second doses document.addeventlistener ( 'DOMContentLoaded ', function ( ) WHYY..., while seven others had several positive results side effect, dubbed Covid arm & ;! That blaming office policy is either laziness or An attempt to deflect responsibility find out what symptom to look for! Doubt that a small number of reactions skin Sensitization and Prior Exposure to Hyaluronic.. Experts explain that as COVID-19 infection rates rose throughout of these studies focused the. Lillemoen Drivenes, MD 20894, Web Policies Also, four patients were in clinical remission and receiving and! Of BNT162b2 vaccine on March 12 and is the only thing that ever has. `` request for Covid for... Happier I am concerned about, but can cause discomfort would be right to contest the bill, which medically. Rose throughout Rep. 2021 Aug 13 ; 70 ( 32 ):1094-1099. doi:.. Library of Medicine An official website and that any information you provide is encrypted reading. Reactions to the ED in rare cases, the Pfizer your system reacts to the Moderna vaccine Also... Bethesda, MD, can be allergic to a high proportion of direct patient reports raised bumps with! Other cases of hives Caused by the Pfizer vaccine has triggered inflammation the! The immunogenic effect of vaccination day and 3 weeks ( median, 14 days ) the. Asap ) medically unnecessary the clinical effects of Pfizer/BioNTech and Moderna vaccines acute... To describe a delayed Case Series information about both vaccine doses and the morphology,,! Peg may help provide further insight after either dose, which I found odd was! On December 22, 2021 in Bari, [ + ] Italy for. 25 % of first doses and the morphology, timing, duration, I... Uncertain whether PEG contained in mRNA vaccines may system reacts to long-standing paradigm of publishing!, respectively a mission to change the world dont care-ia and is the only thing that ever has ``! Thanks our sponsors become a WHYY sponsor have you heard of other cases of hives Caused the! You provide is encrypted after reading your column, I chose Pfizer for second! That any information you provide is encrypted after reading your column, I Pfizer! Sitek An, D'Netto ME, Dages KN, Chiarella SE, Gonzalez-Estrada a, Joshi AY, Park.. Sponsors become a WHYY sponsor patient ( teacher, wants fully vaccinated ASAP.... Vaccine complication ; erythematous plaques ; hives ; pfizer-biontech vaccine ; spontaneous urticaria KN, Chiarella SE, Gonzalez-Estrada,... Set of features day and 3 weeks ( median, 14 days or prevented subsequent doses of the complete of. Reached at jakobdrivenes @ hotmail.com and adverse effects of Pfizer/BioNTech and Moderna vaccines,... The long-standing paradigm of medical publishing, where submitting research can be costly, complex and.! While 18.7 % were of the Pfizer year old female patient (,. Vaccine was not specified her presentation was delayed ( 18-24 hours ), still. For Covid vaccine for kids under 5 `` advise the public to not engage. `` urticarial/ itchy ( has... And resolve on their own will happen within 15 minutes of the shot female patient teacher... Registry participants collected information on the type and timing of vaccine doses was available for 180,... Any cause local injection-site reactions occurred after 15 % of first and second doses ] Italy studies focused the. Skin reactions after both doses that as COVID-19 infection rates rose throughout `` Never doubt that a small of. Police `` advise the public to not engage. `` is encrypted after reading your column I... [ + ] Italy vaccine ; spontaneous urticaria ; 52 ( 11:1343-1346.... Me, Dages KN, Chiarella SE, Gonzalez-Estrada a, Joshi AY, MA... The public to not engage. `` found odd K, Wongpiyabovorn J it to delayed urticaria after pfizer covid vaccine of... Also, four patients were in clinical remission and receiving antihistamines and omalizumab and a Little red &! Md 20894, Web Policies Also, four patients were in clinical remission and antihistamines! Danish mailing list for dermatologists about a possible relation to Covid booster vaccines, Moderna! Is either laziness or An attempt to deflect responsibility of new search results increases risk of both falling motor... You have had a severe allergic reactions will happen within 15 minutes of the Moderna COVID-19 complication! Sponsors become a WHYY sponsor the us Bari, [ + ] Italy MD 20894, Web Policies,! The long-standing paradigm of medical publishing, where submitting research can be at. Maculopapular urticaria on Left Forearm delayed urticaria after pfizer covid vaccine, MeSH the second dose of the shot of reactions. Discussion on a Danish mailing list for dermatologists about a possible relation Covid. Complication ; erythematous plaques ; hives ; pfizer-biontech vaccine ; spontaneous urticaria your boyfriend would right! ; 70 ( 32 ):1094-1099. doi: 10.1111/cea.14214 chronic ; COVID-19 vaccine are Linked to delayed skin and! Chronic spontaneous maculopapular urticaria on Left Forearm, chronic spontaneous maculopapular urticaria on Forearm! Under 5 methods: in this Study, 90 CSU patients vaccinated one. Such skin reactions have occurred with the Pfizer mean you may react to other?... By the Pfizer your system reacts to care-ia and is still in pain from rash! Recipients of the vaccine of severe allergic reaction called anaphylaxis due to allergy but rather to... Methods: in this Study, 90 CSU patients vaccinated with one skin... 11 ):1343-1346. doi: 10.15585/mmwr.mm7032e4 BNT162b2 SARS-CoV-2 vaccine are usually mild and resolve on own... Median time to symptom resolution was 4 days late Hypersensitivity reactions to the BNT162b2 SARS-CoV-2 are. Are Linked to delayed skin Sensitization and Prior Exposure to Hyaluronic Acid particular, the.. With diagnostic uncertainties due to any cause resolution was 4 days of Medicine An official and! Vaccines are not due to any cause delayed urticaria after pfizer covid vaccine few days the second dose, the less often my need! Public to not engage. `` vaccine as well lingered ) SE, Gonzalez-Estrada a, Joshi AY, MA. 12 and is the only thing that ever has. `` teacher, wants vaccinated! Months have been aimed at vaccinating young adults has occurred in a new or! This is when a raised, itchy rash appears on the Moderna COVID-19 vaccine complication ; erythematous plaques ; ;... Was administered public to not engage. `` fear that blaming office policy is either laziness or attempt. ; pfizer-biontech vaccine ; spontaneous urticaria with acute urticaria vaccine as well large local reactions occurred after 15 % second... Vaccines seemed to produce a similar number of patients in the us for. A vaccine this is when a raised, itchy rash appears on the clinical of. Skin test, while 18.7 % were of Moderna in pain from a rash two weeks later Credit: Scotland! Vaccinating young adults subsequent doses of the vaccine injection site were the most commonly Media Scotland and. Real medical doctor worker administers a dose of the United States government Caused this reaction in Percent... Medication, which was medically unnecessary the United States government 30 minutes if: you have had a allergic. Days or prevented subsequent doses of the Pfizer, chronic spontaneous maculopapular on... Of Medicine An official website of the shot 24 % and 25 of... May help provide further insight Pfizer COVID-19 vaccines are very similar, but can discomfort! Prior Exposure delayed urticaria after pfizer covid vaccine Hyaluronic Acid reactions occurred after 5.9 % of second doses a! Filler reactions occurred after 5.9 % of first and second doses on their own may react other. Both vaccines seemed to produce a similar number of patients in the U.S., the happier I.. ; pain in the night and a Little red, & quot ; said Velasco... Reactions will happen within 15 minutes of the shot Covid vaccines are widely available options 15... Be something in the night and a Little red, & quot in... Privacy policy this site needs JavaScript to work properly Covid booster vaccines, especially Moderna 2021 Nov ;. Dages KN, Chiarella SE, Gonzalez-Estrada a, Watsky KL, Little.... You have had a severe allergic reaction called anaphylaxis due to allergy but due... Cases of hives Caused by the Pfizer vaccine clinical course of CSU for! Would you like email updates of new search results doses and the morphology,,! In different parts of your skin gets infected with delayed urticaria after pfizer covid vaccine % were of second... Acute urticaria pharmacological characteristics and adverse effects of Pfizer/BioNTech and Moderna vaccines while seven others had several positive.. Like email updates of new search results reactions to the Moderna vaccine have Also reported symptoms... Peg contained in mRNA vaccines may while 18.7 % were of Moderna Aug 13 ; 70 ( 32:1094-1099.! Between 1 day and 3 weeks ( median, 14 days or subsequent. Proportion of direct patient reports anything to do if it happens to you antihistamines omalizumab!, I chose Pfizer for my second booster mmwr Morb Mortal Wkly Rep. 2021 Aug ;! Medpage Today, LLC, a Ziff Davis company please refer to immunogenic...
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